KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP6
All Species:
23.64
Human Site:
Y363
Identified Species:
57.78
UniProt:
Q16828
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16828
NP_001937.2
381
42320
Y363
R
V
P
A
Q
Q
L
Y
F
T
T
P
S
N
Q
Chimpanzee
Pan troglodytes
XP_526209
468
50775
Y450
H
A
S
S
E
Q
L
Y
F
S
T
P
T
N
H
Rhesus Macaque
Macaca mulatta
XP_001091142
368
40570
Y350
H
A
P
S
E
Q
L
Y
F
S
T
P
T
N
H
Dog
Lupus familis
XP_852241
381
42285
Y363
R
V
P
A
Q
Q
L
Y
F
T
T
P
S
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBB1
381
42389
Y363
R
V
P
T
P
Q
L
Y
F
T
T
P
S
N
Q
Rat
Rattus norvegicus
Q64346
381
42300
Y363
R
V
P
A
Q
Q
L
Y
F
T
A
P
S
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506331
383
42666
Y365
H
V
P
S
E
Q
L
Y
F
T
T
P
T
N
H
Chicken
Gallus gallus
Q9PW71
375
41034
H356
F
P
V
S
V
G
V
H
A
T
P
S
S
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001163824
383
42813
P363
R
I
S
A
P
S
Q
P
L
Y
F
T
T
P
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794377
403
44845
G340
T
C
R
C
A
I
D
G
C
H
C
L
S
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
70
99.7
N.A.
98.1
98.6
N.A.
71
37.5
N.A.
N.A.
80.4
N.A.
N.A.
N.A.
45.4
Protein Similarity:
100
70.3
83.4
100
N.A.
98.9
99.4
N.A.
86.6
53.8
N.A.
N.A.
88.7
N.A.
N.A.
N.A.
59.3
P-Site Identity:
100
46.6
53.3
100
N.A.
86.6
93.3
N.A.
66.6
13.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
73.3
80
100
N.A.
86.6
93.3
N.A.
86.6
33.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
40
10
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
10
0
10
0
0
0
0
10
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
70
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% G
% His:
30
0
0
0
0
0
0
10
0
10
0
0
0
0
30
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
70
0
10
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% N
% Pro:
0
10
60
0
20
0
0
10
0
0
10
70
0
20
10
% P
% Gln:
0
0
0
0
30
70
10
0
0
0
0
0
0
0
40
% Q
% Arg:
50
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
20
40
0
10
0
0
0
20
0
10
60
0
0
% S
% Thr:
10
0
0
10
0
0
0
0
0
60
60
10
40
0
10
% T
% Val:
0
50
10
0
10
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _